Stephen Epstein (born December 1935) is a board-certified American cardiologist in Washington, D.C. He is the Head of Translational and Vascular Biology Research at the MedStar Heart and Vascular Institute, MedStar Washington Hospital Center and Clinical Professor of Medicine at the Georgetown University School of Medicine.
Stephen Epstein Facts
- Full Name: Stephen Edward Epstein
- Age: 86 years old
- Date of Birth: December 1935
- Occupation: Cardiologist
- Nationality: American
Stephen Epstein Medical School & Residency
- Clinical Center at the National Institutes of Health – Residency, Internal Medicine, 1963-1965
- New York Presbyterian Hospital (Cornell Campus) – Residency, Internal Medicine, 1961-1963
- Weill Cornell Medicine – Medical School
Stephen Epstein Career
At the National Institutes of Health in Bethesda, Maryland, Epstein held the position of Chief of the Cardiology Branch of the NHLBI for more than 30 years. At the MedStar Health Research Institute, Washington Hospital Center, he held the positions of Executive Director of the Cardiovascular Research Institute and Director of Vascular Biology Research.
Epstein is a renowned expert in angiogenesis and the use of stem cell techniques for cardiovascular therapies, with more than 500 articles in peer-reviewed medical journals. Mesenchymal stem cells (MSCs), when given intravenously to mice with acute myocardial infarction and mice with ischemic cardiomyopathy, significantly slow down the progressive development of adverse left ventricular remodeling and decline in LV function, according to his most recent research on stem cell therapy.
He and his colleagues have also shown that a reduction of the excessive immunological and inflammatory responses that are brought on by the presence of a damaged left ventricle is one of the mechanisms underlying these advantageous effects.
These findings led to the beginning of two clinical trials examining the effectiveness of injecting MSCs intravenously in heart failure patients. In order to treat patients with myocardial infarctions, heart failure, and a variety of autoimmune illnesses, innovative monoclonal antibody techniques to control inflammation are now being developed using the data as a guide.
A biomarker method created by Epstein and his colleagues identifies people with coronary artery disease who are at extremely high short-term risk of passing away or suffering an acute myocardial infarction.
Epstein served on two National Heart, Lung, and Blood Institute (NHLBI) committees: as Chairman of the DSMB for Specialized Centers for Clinically Oriented Research in Cardiac Dysfunction and Disease and Vice-Chairman of the DSMB for Programs of Excellence in Gene and Cell Therapy for the NHLBI.
Epstein also holds honorary fellowships in the American College of Chest Physicians and the American Heart Association. He is a member of the Association of American Physicians. The Pfizer Visiting Professor Program chose him, and he is the recipient of the Distinguished WELCOME Lecturer award.
Certifications & Licensure
- DC State Medical License – Active through 2020
- MedStar Washington Hospital Center, Washington, DC
Location & Contact Information
Medstar Washington Hospital Center
110 Irving St NW
Washington, DC 20010
Fax: (202) 287-7731