Home Symptoms High Blood Protein – 10 Causes, Diagnosis & Treatment

High Blood Protein – 10 Causes, Diagnosis & Treatment

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A high blood protein level (hyperproteinemia) is an abnormally high level of protein in the bloodstream. Although elevated blood protein is not a specific disease or condition in and of itself, it may signal that you have one.

Albumin and globulins are the two major types of proteins found in the blood. Blood proteins assist your body in producing the substances it requires to function properly. Hormones, enzymes, and antibodies are examples of these substances.

Hyperproteinemia is not a distinct disease or condition in and of itself. Typically, it is a laboratory finding that is discovered during the investigation of a specific condition or symptom. For example, while dehydrated individuals have elevated blood protein levels, the fundamental issue is that their blood plasma is more concentrated.

Certain proteins in the blood may be raised as a result of your body’s response to an infection or other type of inflammation. Certain bone marrow diseases, such as multiple myeloma, may cause elevated blood protein levels before any other symptoms manifest.

Causes of High Blood Protein

Conditions that can result in elevated serum protein include:

  • Multiple myeloma
  • Sarcoidosis
  • Chronic (long-term) inflammation or inflammatory disorders
  • Waldenstrom macroglobulinemia
  • Hepatitis B
  • Hepatitis C
  • Dehydration
  • Severe liver disease
  • Severe kidney disease


A blood test reveals whether or not there is an abnormally high level of protein in the blood. Protein levels are frequently included in a comprehensive metabolic panel, a blood test that doctors prescribe as part of a comprehensive checkup. A blood sample is obtained by the health professional using a tiny needle placed into a vein in your arm. The blood sample is analyzed in a laboratory to determine the amount of total protein in your body, among other things.

Blood test results frequently include total protein concentrations, albumin concentrations, and albumin to globulin ratio. An abnormal blood protein level may necessitate additional testing, such as protein electrophoresis and quantitative immunoglobulins.


Treatment for elevated blood protein levels is determined by the underlying cause. For instance, if you have hyperproteinemia as a result of mild dehydration, your doctor may advise you to increase your fluid intake and then recheck your blood.

Doctors address elevated blood protein levels caused by different medical problems based on the cause and severity of the problem.

Consult your doctor if a blood test reveals an elevated blood protein level. Ensure that you receive any additional testing recommended by your doctor. Keep all follow-up appointments. Follow-up treatment can assist in ensuring that the underlying problem is effectively addressed and in re-evaluating the need for additional blood testing.


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