Home People Douglas Sawyer – Biography, Age, Medical Education, Career & Net Worth

Douglas Sawyer – Biography, Age, Medical Education, Career & Net Worth

Douglas Sawyer (born May 19, 1962) is a board-certified American cardiologist in Portland, Maine. He is the Chief of Cardiac Services, Maine Medical Center.

Douglas Sawyer

Douglas Sawyer Facts

  • Full Name: Douglas Brian Sawyer
  • Age: 60 years old
  • Date of Birth: May 19, 1962
  • Place of Birth: Cape Eliz, Maine
  • Occupation: Cardiologist
  • Nationality: American

Douglas Sawyer Medical School & Residency

  • Brigham and Womens Hospital, Fellowship Hospital — 1997
  • Brigham and Womens Hospital, Residency Hospital — 1994
  • Brigham and Womens Hospital, Internship Hospital — 1993
  • Weill Cornell Medical, Medical School — 1991

Douglas Sawyer Career

Douglas Sawyer is a cardiologist and cell biologist whose research focuses on the maintenance and repair processes of the adult heart. How neuregulin and the erbB2 and erbB4 receptors govern the adult heart’s response to damage is a subject of great study. His research has used a number of animal and tissue culture models to illustrate the significance of neuregulin as a growth and survival factor involved in heart homeostasis.

This research has helped to the development of neuregulin-1 as a potential heart disease treatment. His research has also discovered exercise as a physiological regulator of neuregulin biology in mice, and is currently conducting clinical investigations to determine the significance of this finding for exercise’s cardiac effects.

His research has explored the molecular mechanisms by which cancer medicines targeting erbB2 interact with anthracyclines to exacerbate cardiac damage. His research has demonstrated that neuregulin/erbB signaling decreases this cellular damage through a series of fundamental discoveries indicating novel mechanisms of injury induced by anthracycline exposure.

Currently, he is doing clinical research to determine whether these results can be translated into methods to predict which patients treated with these drugs are most likely to develop cardiovascular issues.

Certifications & Licensure

  • American Board of Internal Medicine – Certified in Internal Medicine
  • American Board of Internal Medicine – Certified in Cardiovascular Disease
  • MA State Medical License – Active through 2007
  • TN State Medical License – Active through 2016
  • ME State Medical License – Active through 2024

Hospital Affiliations

  • Maine Medical Center, Portland, ME
  • St. Mary’s Regional Medical Center-Lewiston, Lewiston, ME

Specialty Expertise

Dr. Douglas Brian Sawyer has the following 12 areas of expertise

  • Unstable Angina
  • Heart Failure
  • Stroke
  • Blood Clot
  • Heart Diseases
  • Acute Coronary Syndrome (ACS)
  • Heart Attack
  • Arrhythmia
  • Atherosclerosis
  • Heart Block
  • Hypertension
  • High Cholesterol

Insurance Accepted

  • Anthem Blue Choice PPO – ME
  • Anthem HMO Maine
  • Anthem Pathway – ME
  • Anthem Pathway Enhanced – ME
  • Anthem Pathway X Enhanced/Ind Guided Access ME
  • BCBS Blue Card PPO
  • CIGNA Open Access Plus
  • First Health PPO
  • Harvard Pilgrim ChoiceNet HMO
  • Harvard Pilgrim HMO
  • Harvard Pilgrim Maines Choice HMO
  • Harvard Pilgrim PPO
  • Maine Community Health Options
  • Tufts Granite Advantage EPO, PPO and Saver
  • Tufts Granite Premier Choice EPO and PPO
  • Tufts PPO
  • UHC Choice Plus POS
  • UHC Options PPO

Location & Contact Information

Maine Medical Center
22 Bramhall St
Portland, ME 04102
(207) 662-0111

Fax: (207) 766-2621

Expert Publications

Data provided by the National Library of Medicine

  • Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane.
  • Cytokine-mediated apoptosis in cardiac myocytes: the role of inducible nitric oxide synthase induction and peroxynitrite generation.
  • NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK.
  • Adrenergic overload and apoptosis in heart failure: implications for therapy.
  • High-throughput assessment of calcium sensitivity in skinned cardiac myocytes.
  • Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes.
  • Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes.
    Myocardial hibernation: restorative or preterminal sleep?
  • Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity.
  • The sting of salt on an old, but open, wound–is Na(+) the cause of mitochondrial and myocardial injury during ischemia/reperfusion?
  • Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle.
  • Titin determines the Frank-Starling relation in early diastole.
    Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study.
  • Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta.
  • Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study.

Douglas Sawyer Net Worth

Douglas Sawyer has an estimated net worth of $6 million.


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