Home Drugs Aspirin – Uses, Side Effects & Contraindications

Aspirin – Uses, Side Effects & Contraindications


Acetylsalicylic acid (ASA), also known as aspirin, is a frequently prescribed medication for the treatment of pain and fever resulting from a variety of reasons. Both anti-inflammatory and antipyretic properties are exhibited by acetylsalicylic acid. Additionally, this medication prevents platelet aggregation and is used to treat myocardial infarction, stroke, and blood clots (MI).

Brand Names : Anacin, Arthriten Inflammatory Pain, Ascomp, Aspi-cor, Aspir-low, Bayer Aspirin, Bayer Womens, Bufferin, Duoplavin, Durlaza, Ecotrin, Ecpirin, Equagesic, Exaprin, Excedrin, Excedrin PM Triple Action, Fasprin, Fiorinal, Miniprin, Norgesic Forte, Orphengesic, Pamprin Max Formula, Robaxisal, Trianal, Trianal C, Vanquish, Vazalore, Yosprala.

How Does it Work

Acetylsalicylic acid (ASA) prevents the formation of prostaglandins. For the COX-1 and COX-2 enzymes, it is non-selective. For around 7 to 10 days after COX-1 suppression, platelet aggregation is prevented (average platelet lifespan). The cyclooxygenase-1 (COX-1) enzyme is irreversibly inhibited when the acetyl group of acetylsalicylic acid interacts with a serine residue.

Prostaglandins that cause pain cannot be produced as a result. This procedure also halts the conversion of arachidonic acid to thromboxane A2 (TXA2), a powerful inducer of platelet aggregation Label. Platelet aggregation can cause clots and dangerous venous and arterial thromboembolism, which can result in diseases including pulmonary embolism and stroke.

Aspirin Uses

Doctors usually prescribe Aspirin to treat pain, and reduce fever or inflammation. It is sometimes used to treat or prevent heart attacks, strokes, and chest pain (angina).

Common Side Effects

Frequently reported side effects include: dyspepsia, abdominal or stomach discomfort, heartburn, and nausea.

Others include: black tarry stools, bloody or cloudy urine, change in consciousness, chest pain or discomfort, confusion, constipation, drowsiness, fast breathing, general tiredness and weakness, nervousness, numbness or tingling in the hands, feet, or lips, restlessnesss, skin rash, Reye’s syndrome.


Do not give aspirin to patients with history of asthma or seasonal allergies, stomach ulcers, liver disease, kidney disease, a bleeding or blood clotting disorder, gout, heart disease, high blood pressure, or congestive heart failure.

Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery.

A child or adolescent with a fever, flu-like symptoms, or chickenpox should not be given this medication. Reye’s syndrome, a severe and occasionally fatal illness in children, is a potential side effect of aspirin.



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