Home Drugs Aklief – Drug Uses, Side Effects and Precautions

Aklief – Drug Uses, Side Effects and Precautions


Aklief is an FDA-approved topical medication used to treat acne in adults and children older than 9 years old. It contains an active ingredient called trifarotene.

Generic Nametrifarotene
Dosage Form: Topical Cream
Date of Approval: October 4, 2019
Company: Galderma


Aklief is approved for the treatment of acne in adults and children aged 9 and up.

Acne is a skin disorder that affects a large number of people. When your skin pores become clogged, it causes acne. Acne is most commonly found on the face, but it can also appear on the back, chest, or shoulders.

How To Use Aklief

  • Wash the area where the cream will be applied and pat dry.
  • If you receive a sample tube of Aklief Cream, follow your healthcare provider’s instructions about how much to apply.
  • The cream comes in a pump.
    • Press down on (depress) the pump 1 time to dispense a small amount of Aklief Cream and spread a thin layer over your face (forehead, cheeks, nose, and chin). Avoid contact with your eyes, lips, mouth, and the corners of your nose.
    • Press down on the pump 2 times to dispense enough Aklief Cream to apply a thin layer to cover your upper trunk (the area of your upper back that you can reach, shoulders, and chest). One more pump may be used to apply a thin layer of Aklief Cream to your middle and lower back if acne is present.
  • When you begin treatment with Aklief Cream, you should begin applying a moisturizer on your skin as often as needed.

Side Effects

The following side effects can be associated with taking Aklief. They include mild and severe side effects.

Consult your doctor or pharmacist for further information on potential adverse effects. They can provide you with advice on how to deal with any unpleasant side effects.

Mild side effects include:

  • sunburn
  • dry skin
  • itchy skin
  • mild skin irritation

Severe side effects include:

  • severe skin irritation
  • allergic reaction

Severe side effects are uncommon, but they can happen. If you experience any major side effects, contact your doctor at once. If your symptoms are life-threatening or you believe you’re having a medical emergency, dial 911 or your local emergency number.


  • Limit your time in the sun. Sunlamps, tanning beds, and UV light should be avoided while using Aklief Cream.
  • If you must be in the sun or are sun-sensitive, use sunscreen with a sun protection factor of 15 or higher, as well as protective clothing and a wide-brimmed hat to protect the treated regions.
  • Avoid using Aklief Cream on skin areas with cuts, abrasions, eczema, or sunburned skin.
  • Avoid using skin products that may dry or irritate your skin, such as:
    • medicated or abrasive soaps and cleansers
    • soaps, cleansers, and cosmetics that have strong skin-drying effects
    • products that contain high amounts of alcohol
  • Avoid the use of “waxing” as a hair removal method on skin treated with Aklief Cream.


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